Computational tools create new opportunities for making things, yet designing expressive computational systems poses many challenges. Addressing these challenges requires finding ways to integrate rigorous and structured research and development methodologies with observations of real-world creative production, and dialog and collaboration with different kinds of makers. This course is for Ph.D and Masters students with an interest in researching and designing computational technologies for art, design, manufacturing, or craft. The course is run as a seminar involving discussion of readings and concepts presented in lecture and exploration of human-computer interaction research methodologies.